Slot gambling is a major part of casino games and a major source of gaming revenue and thus tax incomes as well. In the notion of balancing economic benefits and social costs of gambling business, many proactive jurisdictions, such as Australia, Canada and some European countries, have long started to take effective measures to various extents in hope of preventing Problem Gambling of slots from being aggravating. These measures are meant to fulfil the propositions of Responsible Gambling (RG). This paper is not dedicated to the study of the effectiveness of the policies and measures of Responsible Gambling addressing problem gambling of slot games although it lays down some relevant practices adopted in some major jurisdictions. However, it mainly discusses a set of proposed features for slot Responsible Gambling implementation with the state-of-The-Art technology G2S (Gaming to System) from the GSA (Gaming Standards Association), which aims at raising relevant issues and concerns in this rarely discussed topic and providing an initiative for further in-depth empirical and experimental studies. In this paper, some slot Responsible Gambling measures adopted today will be summarized and discussed. Furthermore, the technical aspects will be explored in attaining the requirements of the relevant measures and policies potentially established by regulators and operators.