Caffeine as a photoprotective agent for diminishing phototoxicity

Tong Szeto Yim Tong Szeto; Henry Hy Tong

doi:10.1177/0748233710375947

Caffeine as a photoprotective agent for diminishing phototoxicity

Tong Szeto Yim Tong Szeto
, Henry Hy Tong

Faculty of Health Sciences and Sports

Macau University of Science and Technology

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.

Original language	English
Pages (from-to)	667-670
Number of pages	4
Journal	Toxicology and Industrial Health
Volume	26
Issue number	10
DOIs	https://doi.org/10.1177/0748233710375947
Publication status	Published - Nov 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

5-MOP
Phototoxic
caffeine
comet assay
crosslink

Access to Document

10.1177/0748233710375947

Cite this

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title = "Caffeine as a photoprotective agent for diminishing phototoxicity",

abstract = "Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.",

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AU - Yim Tong Szeto, Tong Szeto

AU - Tong, Henry Hy

PY - 2010/11

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AB - Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.

KW - 5-MOP

KW - Phototoxic

KW - caffeine

KW - comet assay

KW - crosslink

UR - https://www.scopus.com/pages/publications/78650296821

U2 - 10.1177/0748233710375947

DO - 10.1177/0748233710375947

M3 - Article

C2 - 20630985

AN - SCOPUS:78650296821

SN - 0748-2337

VL - 26

SP - 667

EP - 670

JO - Toxicology and Industrial Health

JF - Toxicology and Industrial Health

IS - 10

ER -

Caffeine as a photoprotective agent for diminishing phototoxicity

Abstract

UN SDGs

Keywords

Access to Document

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