Climate change: approach to intervention using expression vector for carbonic anhydrase via glycosylphosphatidylinositol

Zhang Huili, Kefeng Li, Khue Vu Nguyen

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Climate change is a change in the usual weather found in a place. The climate change has a major impact not only on natural disasters of the Earth but also on human health. The climate crisis is then no longer a future concern. It includes both the global warming driven by human emissions of greenhouse gases (GHG), and the resulting large-scale shifts in weather patterns. Global warming can occur from a variety of causes, both natural and human induced. The primary GHG in Earth’s atmosphere, listed in decreasing order of average global mole fraction, are: water vapor (H2O), carbon dioxide (CO2), methane (CH4), nitrous oxide (N2O), and ozone (O3). Today, scientists around the world continue to try and solve the puzzle of climate change. It is clear that to address climate change, the amount of CO2 released into the atmosphere by industrial process has to be reduced because once it is added to the atmosphere, it can continue to affect climate for thousands of years. For such a purpose, an approach to intervention using expression vectors for any protein targeting to the cell plasma membrane via the glycosylphosphatidylinositol, GPI, anchor is suggested. The resulting GPI-anchored proteins would be useful for studying intermolecular interactions, especially gene-environment interactions, in investigating the potential impact of any chemical compounds on any genes of interest and could be used for carbonic anhydrase (CA)-based CO2-capture (environmental application). This approach would be crucial not only for capturing CO2 via GPI and CA but also for the production of CA enzyme as well as its stabilization and therefore useful for combating the global warming of climate change.

Original languageEnglish
Pages (from-to)134-145
Number of pages12
JournalNucleosides, Nucleotides and Nucleic Acids
Issue number2
Publication statusPublished - 2024
Externally publishedYes


  • CA
  • CA-based CO-capture
  • Climate change
  • GPI
  • carbon dioxide
  • carbonic anhydrase
  • expression vectors
  • gene-environment interactions
  • glycosylphosphatidylinositol


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