Next-generation metabolomics in lung cancer diagnosis, treatment and precision medicine: Mini review

Li Yu, Kefeng Li, Xiaoye Zhang

Research output: Contribution to journalReview articlepeer-review

62 Citations (Scopus)

Abstract

Lung cancer is the leading cause of cancer-related death. Next-generation metabolomics is becoming a powerful emerging technology for studying the systems biology and chemistry of health and disease. This mini review summarized the main platforms of next-generation metabolomics and its main applications in lung cancer including early diagnosis, pathogenesis, classifications and precision medicine. The period covers between 2009 and August, 2017. The major issues and future directions of metabolomics in lung cancer research and clinical applications were also discussed.

Original languageEnglish
Pages (from-to)115774-115786
Number of pages13
JournalOncotarget
Volume8
Issue number70
DOIs
Publication statusPublished - 2017
Externally publishedYes

Keywords

  • Biomarker
  • Lung cancer
  • Next-generation metabolomics
  • Pathogenesis
  • Precision medicine

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