Progress of Drug Nanocrystal Self-Stabilized Pickering Emulsions: Construction, Characteristics In Vitro, and Fate In Vivo

Jifen Zhang, Fangming Dong, Chuan Liu, Jinyu Nie, Shan Feng, Tao Yi

Research output: Contribution to journalReview articlepeer-review

Abstract

A drug nanocrystal self-stabilized Pickering emulsion (DNSPE) is a novel Pickering emulsion with drug nanocrystals as the stabilizer. As a promising drug delivery system, DNSPEs have attracted increasing attention in recent years due to their high drug loading capacity and ability to reduce potential safety hazards posed by surfactants or specific solid particles. This paper comprehensively reviews the progress of research on DNSPEs, with an emphasis on the main factors influencing their construction, characteristics and measurement methods in vitro, and fate in vivo, and puts forward issues that need to be studied further. The review contributes to the advancement of DNSPE research and the promotion of their application in the field of drug delivery.

Original languageEnglish
Article number293
JournalPharmaceutics
Volume16
Issue number2
DOIs
Publication statusPublished - Feb 2024

Keywords

  • characteristic
  • drug delivery
  • fate in vivo
  • nanocrystals
  • Pickering emulsion

Fingerprint

Dive into the research topics of 'Progress of Drug Nanocrystal Self-Stabilized Pickering Emulsions: Construction, Characteristics In Vitro, and Fate In Vivo'. Together they form a unique fingerprint.

Cite this