Reproducibility of cardiac biomarkers response to prolonged treadmill exercise

Ye Tian; Jinlei Nie; Keith P. George; Chuanye Huang

doi:10.3109/1354750X.2014.880855

Reproducibility of cardiac biomarkers response to prolonged treadmill exercise

Ye Tian
, Jinlei Nie
, Keith P. George
, Chuanye Huang

Faculty of Health Sciences and Sports

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We examined the reproducibility of alterations in cardiac biomarkers after two identical bouts of prolonged exercise in young athletes. Serum high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were assessed before and after exercise. Significant rises in median hs-cTnT and NT-proBNP occurred in both trials. While the absolute changes in hs-cTnT were smaller after trial 2, the pattern of change was similar and the delta scores were significantly related. However, the change in NT-proBNP was not correlated between trials. The hs-cTnT release demonstrates some consistency after exercise although the blunted hc-cTnT response requires further study.

Original language	English
Pages (from-to)	114-120
Number of pages	7
Journal	Biomarkers
Volume	19
Issue number	2
DOIs	https://doi.org/10.3109/1354750X.2014.880855
Publication status	Published - Mar 2014

Keywords

Cardiac function
Endurance run
Highly sensitive cardiac troponin T
N-terminal pro-B-type natriuretic peptide

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10.3109/1354750X.2014.880855

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title = "Reproducibility of cardiac biomarkers response to prolonged treadmill exercise",

abstract = "We examined the reproducibility of alterations in cardiac biomarkers after two identical bouts of prolonged exercise in young athletes. Serum high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were assessed before and after exercise. Significant rises in median hs-cTnT and NT-proBNP occurred in both trials. While the absolute changes in hs-cTnT were smaller after trial 2, the pattern of change was similar and the delta scores were significantly related. However, the change in NT-proBNP was not correlated between trials. The hs-cTnT release demonstrates some consistency after exercise although the blunted hc-cTnT response requires further study.",

keywords = "Cardiac function, Endurance run, Highly sensitive cardiac troponin T, N-terminal pro-B-type natriuretic peptide",

author = "Ye Tian and Jinlei Nie and George, \{Keith P.\} and Chuanye Huang",

note = "Funding Information: The study was supported by a research grant from National Science and Technology Ministry of China (Study on the Key Factors in Potential Gold Medal Events for Elite Athletes, No. 2006BAK37B00).",

year = "2014",

month = mar,

doi = "10.3109/1354750X.2014.880855",

language = "English",

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pages = "114--120",

journal = "Biomarkers",

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T1 - Reproducibility of cardiac biomarkers response to prolonged treadmill exercise

AU - Tian, Ye

AU - Nie, Jinlei

AU - George, Keith P.

AU - Huang, Chuanye

N1 - Funding Information: The study was supported by a research grant from National Science and Technology Ministry of China (Study on the Key Factors in Potential Gold Medal Events for Elite Athletes, No. 2006BAK37B00).

PY - 2014/3

Y1 - 2014/3

N2 - We examined the reproducibility of alterations in cardiac biomarkers after two identical bouts of prolonged exercise in young athletes. Serum high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were assessed before and after exercise. Significant rises in median hs-cTnT and NT-proBNP occurred in both trials. While the absolute changes in hs-cTnT were smaller after trial 2, the pattern of change was similar and the delta scores were significantly related. However, the change in NT-proBNP was not correlated between trials. The hs-cTnT release demonstrates some consistency after exercise although the blunted hc-cTnT response requires further study.

AB - We examined the reproducibility of alterations in cardiac biomarkers after two identical bouts of prolonged exercise in young athletes. Serum high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were assessed before and after exercise. Significant rises in median hs-cTnT and NT-proBNP occurred in both trials. While the absolute changes in hs-cTnT were smaller after trial 2, the pattern of change was similar and the delta scores were significantly related. However, the change in NT-proBNP was not correlated between trials. The hs-cTnT release demonstrates some consistency after exercise although the blunted hc-cTnT response requires further study.

KW - Cardiac function

KW - Endurance run

KW - Highly sensitive cardiac troponin T

KW - N-terminal pro-B-type natriuretic peptide

UR - https://www.scopus.com/pages/publications/84894525205

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DO - 10.3109/1354750X.2014.880855

M3 - Article

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SN - 1354-750X

VL - 19

SP - 114

EP - 120

JO - Biomarkers

JF - Biomarkers

IS - 2

ER -

Reproducibility of cardiac biomarkers response to prolonged treadmill exercise

Abstract

Keywords

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