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UA-MAE: An Uncertainty-Aware Masked Autoencoder for Breast Lesion Segmentation in Ultrasound Images

  • Xiangyu Xiong
  • , Yue Sun
  • , Jiaju Huang
  • , Da Huang
  • , Shaobin Chen
  • , Zhuoneng Zhang
  • , Tao Tan
  • Macao Polytechnic University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Accurate segmentation of breast lesions is vital for diagnosing breast diseases. Masked image modeling (MIM) with random masking performs well in self-supervised learning but struggles in breast ultrasound segmentation due to (1) ambiguous representations from similar intensities near lesion boundaries and (2) a bias toward irrelevant regions. We propose UA-MAE, an uncertainty-aware masked autoencoder that uses pixel-wise uncertainty maps to dynamically select masking patches, prioritizing boundaries and morphologically relevant lesion areas. Experiments on two public datasets for pre-training and three for fine-tuning show UA-MAE outperforming four state-of-theart SSL methods and two supervised approaches in segmentation accuracy across diverse breast ultrasound images. The code is available at https://github.com/yXiangXiong/UA-MAE.

Original languageEnglish
Title of host publicationProceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
EditorsJuan Liu, Jingshan Huang, Xiaowo Wang, Fa Zhang, Xiufen Zou, Tian Tian, Xiaohua Hu, Bin Hu, Yi Xiong
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4295-4298
Number of pages4
ISBN (Electronic)9798331515577
DOIs
Publication statusPublished - 2025
Event2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025 - Wuhan, China
Duration: 15 Dec 202518 Dec 2025

Publication series

NameProceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025

Conference

Conference2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
Country/TerritoryChina
CityWuhan
Period15/12/2518/12/25

Keywords

  • Breast ultrasound
  • Masked autoencoders
  • Segmentation
  • Self-supervised learning
  • Uncertainty map

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