UltraTwin: Towards Cardiac Anatomical Twin Generation from Multi-view 2D Ultrasound

Junxuan Yu, Yaofei Duan, Yuhao Huang, Yu Wang, Rongbo Ling, Weihao Luo, Ang Zhang, Jingxian Xu, Qiongying Ni, Yongsong Zhou, Binghan Li, Haoran Dou, Liping Liu, Yanfen Chu, Feng Geng, Zhe Sheng, Zhifeng Ding, Dingxin Zhang, Rui Huang, Yuhang ZhangXiaowei Xu, Tao Tan, Dong Ni, Zhongshan Gou, Xin Yang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Echocardiography is routine for cardiac examination. However, 2D ultrasound (US) struggles with accurate metric calculation and direct observation of 3D cardiac structures. Moreover, 3D US is limited by low resolution, small field of view and scarce availability in practice. Constructing the cardiac anatomical twin from 2D images is promising to provide precise treatment planning and clinical quantification. However, it remains challenging due to the rare paired data, complex structures, and US noises. In this study, we introduce a novel generative framework UltraTwin, to obtain cardiac anatomical twin from sparse multi-view 2D US. Our contribution is three-fold. First, pioneered the construction of a real-world and high-quality dataset containing strictly paired multi-view 2D US and CT, and pseudo-paired data. Second, we propose a coarse-to-fine scheme to achieve hierarchical reconstruction optimization. Last, we introduce an implicit autoencoder for topology-aware constraints. Extensive experiments show that UltraTwin reconstructs high-quality anatomical twins versus strong competitors. We believe it advances anatomical twin modeling for potential applications in personalized cardiac care.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention, MICCAI 2025 - 28th International Conference, 2025, Proceedings
EditorsJames C. Gee, Jaesung Hong, Carole H. Sudre, Polina Golland, Jinah Park, Daniel C. Alexander, Juan Eugenio Iglesias, Archana Venkataraman, Jong Hyo Kim
PublisherSpringer Science and Business Media Deutschland GmbH
Pages608-617
Number of pages10
ISBN (Print)9783032053244
DOIs
Publication statusPublished - 2026
Event28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025 - Daejeon, Korea, Republic of
Duration: 23 Sept 202527 Sept 2025

Publication series

NameLecture Notes in Computer Science
Volume15975 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025
Country/TerritoryKorea, Republic of
CityDaejeon
Period23/09/2527/09/25

Keywords

  • 3D Cardiac Reconstruction
  • Anatomical Twins
  • Diffusion Transformer
  • Multi-view 2D Ultrasound

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