高校男教师良性前列腺增生合并脂肪肝状况及影响因素研究

Background: The incidence of benign prostatic hyperplasia(BPH) or fatty liver disease(FLD) in male university teachers is high,and both diseases are often accompanied.At present,the pathogenesis of the two diseases and the causes of their concomitant diseases are not clear yet.Objective: To explore the prevalence rate of BPH with FLD and its influencing factors among male university teachers,providing a basis for the formulation of targeted prevention and control strategies.Methods: The enrolled 2 136 male university teachers were sampled from individuals undergoing physical examination in the physical examination center of a university hospital in Guangzhou between January 2016 and January 2017,including 500 with BHP(BHP group) and 311 with BHP and FLD (combination group).Clinical data of these two groups were analyzed comparatively.Influencing factors of BHP combined with FLD were analyzed by using multivariate Logistic regression.Results: Totaled 811 cases(38.0%) were found with BHP,311 of whom (38.4%) were identified with FLD.Those with BHP and FLD demonstrated significantly increased mean levels of BMI,urine protein,fasting blood glucose(FBG),urine specific gravity(USG),uric acid(UA),low-density lipoprotein,triacylglycerol(TG),diastolic blood pressure compared with those with BHP (P<0.05).Multivariate Logistic regression analysis showed that increased BMI〔OR=1.447(1.306,1.603),P<0.001〕,FBG〔OR=1.694 (1.365,2.103),P<0.001〕,UA〔OR=1.003(1.000,1.006),P<0.05〕and TG〔OR=1.590 (1.186,2.132),P<0.05〕were risk factors for BHP combined with FLD,while increased high-density lipoprotein was the protective factor for BHP combined with FLD〔OR=0.389(0.162,0.931),P<0.05〕.Conclusion: The prevalence rate of BHP combined with FLD is higher than that of BHP among male university teachers.BMI,FBG,TG,UA and high-density lipoprotein are the influencing factors of BHP combined with FLD.