Caffeine as a photoprotective agent for diminishing phototoxicity

Tong Szeto Yim Tong Szeto; Henry Hy Tong

doi:10.1177/0748233710375947

Caffeine as a photoprotective agent for diminishing phototoxicity

Tong Szeto Yim Tong Szeto
, Henry Hy Tong

Faculty of Health Sciences and Sports

Macau University of Science and Technology

研究成果: Article › 同行評審

7 引文斯高帕斯（Scopus）

摘要

Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.

原文	English
頁（從 - 到）	667-670
頁數	4
期刊	Toxicology and Industrial Health
卷	26
發行號	10
DOIs	https://doi.org/10.1177/0748233710375947
出版狀態	Published - 11月 2010

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10.1177/0748233710375947

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引用此

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title = "Caffeine as a photoprotective agent for diminishing phototoxicity",

abstract = "Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.",

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AB - Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.

KW - 5-MOP

KW - Phototoxic

KW - caffeine

KW - comet assay

KW - crosslink

UR - https://www.scopus.com/pages/publications/78650296821

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EP - 670

JO - Toxicology and Industrial Health

JF - Toxicology and Industrial Health

IS - 10

ER -

Caffeine as a photoprotective agent for diminishing phototoxicity

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