Recent advances in CE-mediated microanalysis for enzyme study

Xu Wang, Kefeng Li, Erwin Adams, Ann Van Schepdael

研究成果: Review article同行評審

47 引文 斯高帕斯(Scopus)

摘要

This review gives an overview of the recent developments and applications in the use of CE-mediated microanalysis for enzyme studies. The period covers mid-2011 until mid-2013. Both off-line and in-line enzyme assays with their applications using CE are described in this article. For the in-capillary enzyme reaction, the techniques using electrophoretically mediated microanalysis (EMMA) as well as immobilized enzyme reactor (IMER) are discussed. The applications include the evaluation of enzyme activity, enzyme kinetics, enzyme inhibition, screening of enzyme inhibitors, and the study of enzyme-mediated drug metabolism.

原文English
頁(從 - 到)119-127
頁數9
期刊Electrophoresis
35
發行號1
DOIs
出版狀態Published - 1月 2014
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